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For the 2025-26 school year, there are 5 public schools serving 1,025 students in Wise, VA (there are , serving 119 private students). 90% of all K-12 students in Wise, VA are educated in public schools (compared to the VA state average of 89%).

The top ranked public schools in Wise, VA are L.f. Addington Middle School and Wise Primary. Overall testing rank is based on a school's combined math and reading proficiency test score ranking.

Wise, VA public schools have an average math proficiency score of 90% (versus the Virginia public school average of 68%), and reading proficiency score of 81% (versus the 70% statewide average). Schools in Wise have an average ranking of 10/10, which is in the top 10% of Virginia public schools.

Minority enrollment is 9% of the student body (majority Hispanic and Black), which is less than the Virginia public school average of 56% (majority Black and Hispanic).