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For the 2025 school year, there are 143 public schools serving 81,578 students in Guilford County, NC (there are , serving 8,077 private students). 91% of all K-12 students in Guilford County, NC are educated in public schools (compared to the NC state average of 92%).

The top ranked public schools in Guilford County, NC are Brown Summit Middle School, Early College At Guilford and Oak Ridge Elementary School. Overall testing rank is based on a school's combined math and reading proficiency test score ranking.

Guilford County, NC public schools have an average math proficiency score of 47% (versus the North Carolina public school average of 51%), and reading proficiency score of 48% (versus the 50% statewide average). Schools in Guilford County have an average ranking of 5/10, which is in the bottom 50% of North Carolina public schools.

Minority enrollment is 72% of the student body (majority Black), which is more than the North Carolina public school average of 57% (majority Black and Hispanic).